Phosphatidic Acid and mTOR, How Are They Essential to Muscle Growth?

Posted March 14, 2016 by Pete Mascioli in Supplements, TGB BLOG 1 0

Phosphatidic Acid and mTOR, How Are They Essential to Muscle Growth?

Phosphatidic Acid and mTOR, How Are They Essential to Muscle Growth? During weight training, your body begins to induce muscle growth by activating mTOR. mTOR is the main enzyme that is responsible for cell protein synthesis which results in hypertrophy. During the eccentric (negative) portion of any exercise, the body releases PA (Phosphatidic Acid) which activates the mTOR.

Studies have shown that 750mg of supplemented PA daily in resistance trained men increased their lean body mass by 50%, increased overall strength by 40% of upper and lower body, and 60% more fat loss than the control group. (Wilson et al 2014)(Hoffman et al. 2013)

So simply put, the more PA that is available to activate mTOR, the greater the effect of protein synthesis within the cell. This allows for a great increase in muscle mass growth and strength. Utilizing just 750mg per day of PA has been shown to have great positive effects on both the skeletal muscle growth and strength.

Find mTOR and PA products here.

-Pete

Hoffman, JR et al. Efficacy of phosphatidic acid ingestion on lean body mass, muscle thickness and strength gains in resistance-trained men. Journal of the International Society of Sports Nutrition. 9:47 2012.