At the heart of berberine’s power is its ability to activate the enzyme AMP-activated protein kinase (AMPK), which is known as the “master metabolic switch”.^†

This enzyme is found in tissues throughout the body, and it plays a major role in regulating metabolism.^†

The issue with berberine is that is has poor solubility and low bioavailability, often requiring large doses to be consumed to derive benefit. In fact, the typical dosage needed for berberine is 500mg taken three times per day (1500mg/day).

While this dose may be effective, it very often leads to GI upset.^†

Diydroberberine is the bioactive metabolite of berberine generated by the gut microbiota, and animal studies note that dihydroberberine has an intestinal absorption rate 5-fold that of berberine.^†

Essentially, dihydroberberine is a more “direct” or “refined” form of berberine that accomplishes the same effects while using a smaller dose and leading to less GI upset.^†

Berberine X5^™ contains GlucoVantage^®, the first commercially available brand of dihydroberberine on the market.

No longer do you have to decide between enjoying the foods you eat or achieving your body composition goals. With Berberine X5^™, you get to have your cake (carbs) and eat it too!